just for reference I he means this one...
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It really depends on the size. I have recently switched to Hitbox for MKx.. I normally am a stick user. The thing is the official hitbox uses non standard button sizes... your hit box looks to be more like normal button sizes.
When I play MKx on stick.. I use this button layout...
1,2,3,I
B,4,T,S
I have always found this super easy to use and be able to easily keep block in a position I can press at all times. The above layout, imo, is the best for stick and gives you such great access to block.
Still the official HitBox is so small that this layout doesn't work... so I use a very traditional layout.
1,2,B,I
3,4,T,S
The thing is though... if you are making it yourself.. why not build the block into it ... maybe in that cross layout?
Something like this...
This is what I would do if I made my own... a X shape, where 1,2,3,4 have all the pros of being close together and 2 finger assessable, and the block is next top all of them.
EDIT... You would need to test.. but I would make something like this if I knew how..
But T,I,S could be moved about.. but you get the idea. You might need to make the block button a little smaller for example, the goal is to get 1,2 and 3,4 close like LP,MP or LK,LK on a stick. So you can easily hit them with your two fingers.
I did experiment with
But there was some strange input things going on like that... Still I get why you are thinking the layout you are.. the big jump button is a perfect spot for the block!